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May localize in: Spleen, Liver, Bone marrow, Joints, Reproductive organs. Severity in humans: B. melitensis>B. suis>B. abortus >B. canis, others. Symptoms-Humans: Common symptoms include Malaise, Insomnia, Anorexia, Headache, Arthralgia, Constipation, sexual impotence, nervousness, depression. (Acha et al., 2003)

#2017#case studies#pathogenesis#mph#p. ryan clarke#dvm#district epidemiologist#u.s. department of agriculture#animal and plant health inspection service#veterinary services#april 3-5#a one health perspective

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